EPILUMINEX® MESOBIOTIX MD
EPIGENETIC LIGHT REPROGRAMMING PROGRAM
Sequential clinical system for melasma and complex hyperpigmentation
is a four-phase topical clinical system designed for the comprehensive management of epidermal and mixed melasma, post-inflammatory hyperpigmentation (PIH), solar lentigines, and uneven tone associated with photoaging.
It is not a conventional cosmetic brightener.
It is a sequential therapeutic architecture that simultaneously intervenes in:
– Melanin synthesis.
– Inflammatory and vascular signaling.
– Melanosome transfer.
– Oxidative stress induced by UV and visible light.
– Skin barrier integrity.
– Prevention of pigmentary rebound.
It integrates active ingredients with the greatest current scientific backing in non-hydroquinone depigmentation, including:
– Cysteamine
– Tranexamic Acid
– Thiazolyl-Resorcinol (Thiamidol-type family)
– 4-Butylresorcinol
– Hexylresorcinol
– Azelaic Acid
– Niacinamide
– N-Acetyl Glucosamine
– Melanogenic precursor modulators (Melanin Pathway Interceptor Technology)
– Advanced antioxidant complex
– Retinoids
– Mesobiotix® biomimetic epigenetic complex
–PDRN (Polydeoxyribonucleotides)
–DEOXYARBUTIN (Advanced generation of arbutin)
CLINICAL INDICATIONS
– Epidermal and mixed melasma.
– Post-inflammatory hyperpigmentation (post-acne, post-procedure).
– Solar lentigines.
– Dyschromia due to photo-damage.
– Uneven or dull tone.
– Patients with a tendency to pigmentary rebound.
It can be used as a primary treatment in mild-moderate cases or as support after procedures once the skin is fully re-epithelialized.
CLINICAL SYSTEM ARCHITECTURE
STEP 1 — EPILUMINEX® GENESIS MB501X
Epigenetic Preparation and Barrier Serum
CLINICAL FUNCTION
Prepare the skin, stabilize the barrier, and reduce subclinical inflammation before introducing high-potency active ingredients.
KEY ACTIVES
– Niacinamide
– N-Acetyl Glucosamine
– Alpha-Arbutin
– Hexylresorcinol
– Ceramide + Cholesterol + Essential Fatty Acids Complex
– Ectoin
– Madecassoside
– Multi-weight Hyaluronic Acid
MECHANISM OF ACTION
– Modulation of melanosome transfer.
– Gentle tyrosinase inhibition.
– Physiological lipid repair.
– Decrease in microinflammation.
DIRECTIONS FOR USE
Morning and night on the entire face before subsequent steps. Do not rinse off.
STEP 2 — EPILUMINEX® MELANO EDIT MB502X
Precision Depigmenting Spot Serum
CLINICAL FUNCTION
Targeted correction of melasma patches and localized spots without overtreating healthy skin.
NEW GENERATION ACTIVES
– Tranexamic Acid
– Thiazolyl-Resorcinol
– 4-Butylresorcinol
– Hexylresorcinol
– Oligopeptide-68
– Diacetyl Boldine
– Niacinamide
– Standardized Licorice Extract
– Melanin Precursor Modulator Technology
– Thiamidol
MECHANISM OF ACTION
– Multiple blockade of melanogenic pathways.
– Interception of pre-melanin intermediates.
– Inflammatory and vascular modulation.
– Reduction of secondary PIH risk.
DIRECTIONS FOR USE
Only at night.
Apply a small amount only on spots after GENESIS MB501X.
Start on alternate nights and adjust according to tolerance.
STEP 3 — EPILUMINEX® LUMINA SHIELD MB503X
Day Barrier and Pigmentation Prevention Cream
CLINICAL FUNCTION
Daytime protective shield that prevents melanocyte reactivation induced by UV, visible light, and oxidative stress.
KEY ACTIVES
– Niacinamide
– Undecylenoyl Phenylalanine
– Stabilized Vitamin C
– Vitamin E + Ferulic Acid
– Resveratrol
– Advanced antioxidant complex
– Lipid barrier complex
–SPF 20
MECHANISM OF ACTION
– Regulation of daytime pro-melanin signals.
– Neutralization of free radicals.
– Continuous reinforcement of the skin barrier.
DIRECTIONS FOR USE
Apply every morning after GENESIS MB501X.
Strictly follow with SPF 50+ photoprotection, reapplying every 2–3 hours.
Iron oxide protection is recommended for melasma patients.
STEP 4 — MB504X — EPIX-4 NIGHT DEPIGM RECODE®
Maximum Depigmentation Night Cream
CLINICAL FUNCTION
Intensive intervention on resistant pigment under professional supervision.
HIGH-POTENCY ACTIVES
– Cysteamine
– Tranexamic Acid
– Thiazolyl-Resorcinol
– 4-Butylresorcinol
– Hexylresorcinol
– Azelaic Acid
– Niacinamide
– Soothing complex (Madecassoside + Beta-Glucan + Bisabolol)
– Melanocytic metabolic modulating technology (inspired by the AMPK pathway)
MECHANISM OF ACTION
– Potent blockade of melanin synthesis.
– Deep inflammatory and vascular modulation.
– Intervention in early stages of melanogenesis.
– Control of pigmentary rebound.
DIRECTIONS FOR USE
Only at night.
Apply after GENESIS MB501X.
Start 2–3 nights per week and scale according to tolerance.
For sensitive skin, maintain an intermittent regimen.
Discontinue in case of significant irritation and continue only with steps 1 and 3 until stabilized.
Do not use during pregnancy or lactation.
BASIC DAY / NIGHT PROTOCOL
MORNING
GENESIS MB501X
LUMINA SHIELD MB503X
Strict SPF 50+ photoprotection
NIGHT
GENESIS MB501X
MELANO EDIT MB502X (focal)
NIGHT DEPIGM RECODE MB504X (as directed)
EXCLUSIVE PROFESSIONAL USE | CE CERTIFICATION | DERMATOLOGICALLY TESTED | MADE IN SPAIN
